- Main article: UMP45 (TLS1)
- Main article: UMP45 (TLS2)
- Main article: UMP45 (TLS:UC)
- Main article: UMP45 (TLS:DZ)
The flagship model of the UMP series that was intended to succeed the MP5. While it has not supplanted its respected predecessor, this gun is a popular weapon in its own right, as it is one of only a few submachine guns designed to fire the intimidating .45 ACP round.
Deployed by law enforcement agencies and specialized military units.